Research Article
Prognostic Index for Nonsmall Cell Lung Cancer Based on Immune-Related Genes Expression
Table 1
Relationships between model variables and clinical variables.
| | Variables | Age (≤65/>65) | Gender (female/male) | Stage (I-II/III-IV) | T (T1-2/T3-4) | M (M0/M1) | N (N0/N1-3) |
| | | | | | | | | THBS1 | 0.452 (0.651) | 1.918 (0.056) | -0.966 (0.336) | -1.187 (0.237) | 1.936 (0.062) | -0.734 (0.463) | | MMP12 | -3.32 (9.509e-04) | -1.659 (0.098) | 1.06 (0.290) | 0.873 (0.384) | 0.068 (0.946) | -0.061 (0.951) | | S100A16 | -2.603 (0.009) | -2.947 (0.003) | -2.127 (0.035) | -1.304 (0.194) | 0.012 (0.990) | -1.59 (0.112) | | PLAU | -3.046 (0.002) | 0.166 (0.868) | -0.599 (0.550) | -2.572 (0.011) | 1.441 (0.160) | 0.482 (0.630) | | CRABP1 | 1.256 (0.210) | 0.745 (0.457) | -0.917 (0.361) | 2.124 (0.034) | -1.167 (0.254) | 1.839 (0.067) | | RBP2 | -1.044 (0.297) | 1.913 (0.057) | 1.37 (0.172) | 0.623 (0.534) | 3.118 (0.002) | 0.629 (0.530) | | NFKBIZ | 0.437 (0.662) | 1.577 (0.115) | 0.868 (0.386) | 0.343 (0.732) | 1.588 (0.123) | 0.637 (0.524) | | DLL4 | 0.92 (0.358) | 3.875 (1.204e-04) | -1.905 (0.058) | 2.003 (0.047) | -0.947 (0.352) | -1.408 (0.160) | | RNASE7 | -1.695 (0.091) | -2.162 (0.031) | 2.742 (0.006) | -1.474 (0.143) | 4.849 (2.731e-06) | 0.735 (0.463) | | IGKV1-6 | -2.26 (0.024) | 0.472 (0.637) | 1.804 (0.072) | 2.309 (0.021) | 1.637 (0.106) | 1.809 (0.071) | | IGLV4-3 | -0.644 (0.520) | 1.028 (0.304) | 0.744 (0.457) | 0.541 (0.589) | 0.038 (0.970) | -0.128 (0.898) | | IGLV4-60 | -0.566 (0.572) | 0.474 (0.636) | -0.166 (0.868) | 0.942 (0.347) | 0.82 (0.418) | 0.255 (0.799) | | SEMA4C | -0.533 (0.595) | 1.161 (0.246) | -1.334 (0.184) | -0.698 (0.486) | 0.771 (0.446) | -1.505 (0.133) | | LTB4R2 | 0.274 (0.784) | -3.348 (8.603e-04) | 2.52 (0.012) | -0.996 (0.321) | 2.552 (0.016) | 0.673 (0.501) | | GREM1 | -0.233 (0.816) | -0.646 (0.518) | 0.494 (0.622) | -0.31 (0.757) | 1.002 (0.325) | -1.157 (0.248) | | IL33 | -0.795 (0.427) | 0.752 (0.452) | 1.411 (0.159) | 1.074 (0.285) | 0.729 (0.471) | 2.886 (0.004) | | INHA | -0.383 (0.702) | 0.611 (0.542) | -2.036 (0.043) | 2.434 (0.015) | -1.987 (0.058) | -0.49 2(0.623) | | JAG1 | -1.526 (0.128) | -4.898 (1.222e-06) | -0.579 (0.564) | -1.352 (0.179) | 1.281 (0.210) | -0.738 (0.461) | | NRTN | 0.492 (0.623) | -1.443 (0.150) | 0.195 (0.846) | -0.309 (0.758) | 1.639 (0.112) | -0.963 (0.336) | | PDGFB | -1.432 (0.153) | -1.556 (0.120) | 1.513 (0.131) | -1.331 (0.186) | 0.848 (0.403) | 1.982 (0.048) | | PNOC | -0.263 (0.793) | 1.816 (0.070) | 1.8 (0.073) | 0.548 (0.585) | 1.215 (0.234) | 2.445 (0.015) | | FGFR4 | 0.23 (0.818) | -1.019 (0.309) | -0.692 (0.490) | 0.228 (0.820) | 0.254 (0.801) | -0.319 (0.750) | | GCGR | 0.352 (0.725) | -0.687 (0.492) | 1.248 (0.212) | 0.448 (0.655) | 4.649 (4.147e-06) | 0.457 (0.648) | | HNF4G | 0.968 (0.334) | 1.35 (0.178) | -0.973 (0.332) | -0.208 (0.835) | -1.328 (0.195) | -0.332 (0.740) | | LGR4 | 0.494 (0.621) | 1.621 (0.106) | -1.264 (0.208) | 0.227 (0.821) | -0.271 (0.789) | -0.361 (0.718) | | SHC3 | 0.95 (0.343) | 4.899 (1.393e-06) | -0.127 (0.899) | -0.456 (0.649) | -0.584 (0.565) | 2.464 (0.014) | | Risk score | -0.649 (0.517) | -0.367 (0.714) | -2.525 (0.013) | -1.215 (0.227) | -1.196 (0.243) | -1.531 (0.127) |
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Note: t: t value from Student’s t-test; : value from Student’s t-test; T: tumor; N: node; M: metastasis. |
