Coronary Artery Bypass Grafting in Patients with Chronic Kidney Disease: Chronic Kidney Disease Has an Independent Adverse Effect on the Long-Term Outcome of Coronary Artery Bypass Grafting
Table 1
Preoperative baseline characteristics of the patients.
Chronic kidney disease (eGFR: mL/min/m2)
G1 ≥90
G2 60–89
G3 30–59
G4 15–29
G5 <15
value
Number of patients
128
1696
576
101
282
eGFR
<0.001
Hemodialysis
0
0
0
0
256(90.8%)
<0.001
Age (years)
<0.001
Male
108 (84.4%)
1361 (80.3%)
501 (87.0%)
80 (79.2%)
231 (81.9%)
0.005
BMI (kg/m2)
<0.001
Dyslipidemia
95 (74.2%)
1310 (77.2%)
414 (71.9%)
83 (82.2%)
187 (66.3%)
<0.001
LDL-cholesterol (mg/dL)
<0.001
Triglyceride (mg/dL)
0.063
Diabetes mellitus
63 (49.2%)
890 (52.5%)
334 (58.0%)
75 (74.3%)
199 (70.6%)
<0.001
Medication
33 (25.8%)
468 (27.6%)
157 (27.3%)
36 (35.6%)
68 (24.1%)
0.282
Insulin user
20 (15.6%)
223 (13.2%)
114 (19.8%)
32 (31.7%)
90 (31.9%)
<0.001
Hemoglobin A1c (%)
0.008
Hypertension
64 (50.0%)
1223 (72.2%)
459 (80.0%)
82 (81.2%)
231 (81.9%)
<0.001
Smoker
82 (56.3%)
1048 (62.0%)
360 (62.8%)
65 (64.4%)
168 (59.6%)
0.594
Chronic lung disease
7 (5.5%)
146 (8.6%)
70 (12.2%)
10 (9.9%)
25 (8.9%)
0.067
Peripheral arterial disease
4 (3.1%)
220 (13.0%)
103 (17.9%)
23 (22.8%)
77 (27.3%)
<0.001
History of stroke/TIA
13 (10.1%)
210 (12.4%)
129 (22.4%)
32 (31.7%)
66 (23.4%)
<0.001
Malignancy
9 (7.0%)
195 (11.5%)
95 (16.5%)
16 (15.8%)
41 (14.5%)
0.004
Collagen disease
5 (3.9%)
30 (1.8%)
15 (2.6%)
7 (6.9%)
7 (2.5%)
0.039
Family history of coronary disease
33 (26.0%)
415 (24.6%)
115 (20.0%)
15 (14.9%)
65 (23.1%)
0.039
Previous myocardial infarction
46 (35.9%)
633 (37.3%)
270 (46.9%)
49 (48.5%)
137 (48.6%)
<0.001
NYHA class
15 (4.2%)
46 (3.6%)
35 (4.6%)
7 (6.7%)
17 (6.1%)
0.033
Class III
35 (9.8%)
148 (11.6%)
91 (11.9%)
17 (16.4%)
52 (18.6%)
Class IV
15 (4.2%)
46 (3.6%)
35 (4.6%)
7 (6.7%)
17 (6.1%)
0.033
Atrial fibrillation
0 (0%)
33 (2.0%)
29 (5.0%)
4 (4.0%)
13 (4.6%)
<0.001
Number of diseased vessels
1VD
10 (7.8%)
82 (4.8%)
21 (3.7%)
2 (2.0%)
11 (3.9%)
0.178
2VD
23 (18.0%)
267 (15.7%)
84 (14.6%)
18 (17.8%)
49 (17.4%)
0.753
3VD
58 (45.3%)
737 (43.5%)
284 (49.3%)
53 (52.5%)
133 (47.2%)
0.075
Left main trunk
37 (28.9%)
607 (35.8%)
185 (32.1%)
28 (27.7%)
87 (30.9%)
0.094
Poor LVEF ()
12 (9.5%)
119 (7.1%)
92 (16.1%)
16 (15.8%)
68 (24.4%)
<0.001
LVEF (%)
<0.001
Mitral regurgitation ()
0 (0%)
33 (2.0%)
20 (3.5%)
10 (9.9%)
15 (5.3%)
<0.001
Preoperative IABP use
5 (3.9%)
66 (3.9%)
23 (4.0%)
7 (6.9%)
14 (5.0%)
0.657
Hemoglobin (g/dL)
<0.001
C reactive protein (mg/dL)
<0.001
Bain natriuretic peptide (pg/mL)
<0.001
Japan score
<0.001
Euroscore II
<0.001
eGFR: estimated glomerular filtration rate; NYHA: New York Heart Association functional classification; 1VD: one-vessel disease; 2VD: two-vessel disease; 3VD: three-vessel disease; LVEF: left ventricular ejection fraction; IABP: intra-aortic balloon pumping; BMI: body mass index.
