Hematological Inflammatory Markers in Patients with Clinically Confirmed Familial Hypercholesterolemia
Table 1
Demographical, clinical, and biochemical characteristics of FH and non-FH patients.
Parameter
FH group
value
FH group
value
Non-FH (473)
Possible (813)
Definite and probable (261)
FH (1074)
Non-FH
Age
<0.001
<0.001
Sex (male)
281 (59.4)
452 (55.7)
110 (42.1)
<0.001
562 (52.4)
281 (59.4)
0.011
Smoking (smokers)
49 (10.4)
133 (16.4)
29 (11.1)
0.004
162 (15.1)
49 (10.4)
0.013
HTN
144 (30.5)
348 (43.0)
88 (34.5)
<0.001
436 (40.9)
144 (30.5)
<0.001
Type2-DM
57 (12.1)
170 (21.1)
58 (23.3)
<0.001
228 (21.6)
57 (12.1)
<0.001
CVD history
139 (29.4)
432 (53.2)
124 (47.5)
<0.001
556(51.8)
139 (29.4)
<0.001
Aspirin use
117 (39.9)
284 (77.2)
63 (67.0)
<0.001
347 (75.1)
117 (39.9)
<0.001
Antilipid drug
178 (37.9)
495 (64.0)
180 (77.3)
<0.001
675 (67.0)
178 (37.9)
<0.001
BMI (kg/m2)
0.015
0.002
Total cholesterol (mg/dl)
<0.001
<0.001
LDL (mg/dl)
<0.001
<0.001
Triglyceride (mg/dl)
0.009
0.032
HDL (mg/dl)
0.021
0.086
HDL/LDL ratio
<0.001
<0.001
Data are shown as frequency (percentage). Chi-square test was used. Data are shown as . Independent sample -test or one-way analysis of variance was used. Linear random intercept model was used.
