Synthesis, Carbonic Anhydrase II/IX/XII Inhibition, DFT, and Molecular Docking Studies of Hydrazide-Sulfonamide Hybrids of 4-Methylsalicyl- and Acyl-Substituted Hydrazide

Table 2

Physical data of sulfonamides (19-36).

Sr. no.	Structure	mp (°C)		Yield (%)
19		220-222	0.5	89
20		168-169	0.4	85
21		159-162	0.3	83
22		161-163	0.4	76
23		186-187	0.4	79
24		211-213	0.2	82
25		231-215	0.3	81
26		168-169	0.2	75
27		183-185	0.3	85
28		205-206	0.5	85
29		156-157	0.5	70
30		133-134	0.3	82
31		143-144	0.4	80
32		158-159	0.4	76
33		153-154	0.4	80
34		146-147	0.2	70
35		143-144	0.3	87
36		139-141	0.5	84