Research Article

Synthesis, Carbonic Anhydrase II/IX/XII Inhibition, DFT, and Molecular Docking Studies of Hydrazide-Sulfonamide Hybrids of 4-Methylsalicyl- and Acyl-Substituted Hydrazide

Table 4

Ki values and inhibition percentages of the synthesized compounds against CA II, CA IX, and CA XII.

Sr no.CAIICAIXCAXII
Ki ()/% inhibition

1944.4%
20
21
2242.89%
23
24
25
26
27
28
29
30
31
3249.25%
33
34
35
3648.88%
Acetazolamide