ESM1 Is a Promising Therapeutic Target and Prognostic Indicator for Esophageal Carcinogenesis/Esophageal Squamous Cell Carcinoma

Table 3

The associations between ESM1 expression and clinicopathological characteristics in 83 ESCC patients. and .

Characteristics		ESM1 expression
		Low ((%))	High ((%))
All	83	54 (65.1)	29 (34.9)
Age (year)				2.263	0.132
<60	32	24 (44.4)	8 (27.6)
≥60	51	30 (55.6)	21 (72.4)
Gender				0.813	0.367
Male	54	37 (68.5)	17 (58.6)
Female	29	17 (31.5)	12 (41.4)
Tumor size (cm^3)				1.116	0.291
<5	10	8 (14.8)	2 (6.9)
≥5	73	46 (85.2)	27 (93.1)
T classification				3.009	0.390
Tis	1	1 (1.9)	0 (0)
T1	3	2 (3.7)	1 (3.4)
T2	16	13 (24.1)	3 (10.3)
T3	63	38 (70.4)	25 (86.2)
N classification				7.775	0.005
N0	44	35 (64.8)	9 (31.0)
N1	31	15 (27.8)	16 (55.2)
N2	6	4 (7.4)	2 (6.9)
N3	2	0 (0)	2 (6.9)
M classification				—	—
M0	83	54	29
M1	0	0	0
pTNM stage				4.219	0.04
I+II	47	35 (64.8)	12 (41.4)
III+IV	36	19 (35.2)	17 (58.6)
Pathological differentiation				5.608	0.132
High differentiation	8	8 (14.8)	0 (0)
Middle differentiation	58	36 (66.7)	22 (75.9)
Low differentiation	16	9 (16.7)	7 (24.1)
Undifferentiated	1	1 (1.9)	0 (0)
Tumor embolus				0.522	0.47
Negative	78	50 (92.6)	28 (96.6)
Positive	5	4 (7.4)	1 (3.4)