ESM1 Is a Promising Therapeutic Target and Prognostic Indicator for Esophageal Carcinogenesis/Esophageal Squamous Cell Carcinoma

Table 4

Univariate and multivariate Cox regression analyses of overall survival in 83 patients with ESCC. and .

Parameter	Overall survival
	Univariate analysis		Multivariate analysis
	HR (95% CI)		HR (95% CI)
Age	4.287 (1.262-14.564)	0.02	3.225 (0.937-11.095)	0.063
Gender	0.738 (0.311-1.751)	0.49	--	--
Tumor size	1.526 (0.355-6.556)	0.57
T classification	3.155 (0.817-12.181)	0.095
N classification	2.055 (1.321-3.197)	0.001	1.38 (0.616-3.094)	0.434
pTNM stage	2.663 (1.543-4.594)	≤0.001	2.031 (1.039-3.972)	0.038
Pathological differentiation	1.468 (0.697-3.094)	0.312	--	--
Tumor embolus	2.223 (0.517-9.555)	0.283
IHC score-ESM1	2.425 (1.027-5.726)	0.043	1.506 (0.634-3.578)	0.353