Ureterorenoscopic (URS) Lithotripsy and Balloon Dilation Cause Acute Kidney Injury and Distal Renal Tubule Damage: A Prospective Study

Table 2

The impact of hydronephrosis on kidney injury, evaluated by acute kidney injury (AKI) maker (NGAL) and renal tubular damage markers (αGST and πGST) in group 1 (ureteral stricture) and group 2 (ureteral stone) at baseline compared to the negative controls (NC).

(a)

Part 1. Compared with negative control (NC)
NGAL	value		value
Stone H0 vs. NC	0.456
Stone H1 vs. NC	0.153	Stricture H1 vs. NC	0.113
Stone H2 vs. NC	0.035	Stricture H2 vs. NC	0.390
Stone H3 vs. NC	0.006	Stricture H3 vs. NC	0.007
αGST
Stone H0 vs. NC	0.241
Stone H1 vs. NC	0.058	Stricture H1 vs. NC	0.385
Stone H2 vs. NC	0.002	Stricture H2 vs. NC	0.848
Stone H3 vs. NC	0.000	Stricture H3 vs. NC	0.352
πGST
Stone H0 vs. NC	0.332
Stone H1 vs. NC	0.059	Stricture H1 vs. NC	0.080
Stone H2 vs. NC	0.007	Stricture H2 vs. NC	0.604
Stone H3 vs. NC	0.000	Stricture H3 vs. NC	0.440

(b)

Part 2. Comparison between ureteral stone (group 2) and ureteral stricture (group 1)
NGAL	value
Stone H1 vs. stricture H1	0.153
Stone H2 vs. stricture H2	0.219
Stone H3 vs. stricture H3	0.452
αGST
Stone H1 vs. stricture H1	0.064
Stone H2 vs. stricture H2	0.000
Stone H3 vs. stricture H3	0.000
πGST
Stone H1 vs. stricture H1	0.051
Stone H2 vs. stricture H2	0.003
Stone H3 vs. stricture H3	0.000

Abbreviations: NC: negative control; H0: grade 0 hydronephrosis; H1: grade 1 hydronephrosis; H2: grade 2 hydronephrosis; H3: grade 3 hydronephrosis.
Bold value represents statistically significant .