Identification of a Five-Gene Panel to Assess Prognosis for Gastric Cancer

Table 3

Potential driver genes significantly associated with gastric cancer recurrence and verified by Fisher’s exact test.

Gene name	Cytogenetic band	Description	Ensembl ID	values
TTN	2q31.2	Titin	ENSG00000155657	0.0001441
KNL1	15q15.1	Kinetochore scaffold 1	ENSG00000137812	0.005038
C6	5p13.1	Complement C6	ENSG00000039537	0.01131
NRXN1	2p16.3	Neurexin 1	ENSG00000179915	0.01192
CCDC169-SOHLH2	13q13.3	Spermatogenesis and oogenesis specific basic helix-loop-helix 2 coiled-coil domain containing 169	ENSG00000250709	0.01255
KRAS	12p12.1	KRAS protooncogene, GTPase	ENSG00000133703	0.02746
TSPOAP1	17q22	TSPO-associated protein 1	ENSG00000005379	0.03608
DNAH9	17p12	Dynein axonemal heavy chain 9	ENSG00000007174	0.03468
MAP7D1	1p34.3	MAP7 domain containing 1	ENSG00000116871	0.03282
NCKAP5	2q21.2	NCK-associated protein 5	ENSG00000176771	0.02106
PREX2	8q13.2	Phosphatidylinositol-3,4,5-trisphosphate-dependent Rac exchange factor 2	ENSG00000046889	0.01929
SMG1	16p12.3	SMG1 nonsense mediated mRNA decay associated PI3K-related kinase	ENSG00000157106	0.03282
TNKS1BP1	11q12.1	Tankyrase 1 binding protein 1	ENSG00000149115	0.01931
ABCB4	7q21.12	ATP binding cassette subfamily B member 4	ENSG00000005471	0.02506
ALK	2p23.2-p23.1	ALK receptor tyrosine kinase	ENSG00000171094	0.02106
ATXN1	6p22.3	Ataxin 1	ENSG00000124788	0.0488
ASTN2	9q33.1	Astrotactin 2	ENSG00000148219	0.01718
C2ORF16	2p23.3	Chromosome 2 open reading frame 16	ENSG00000221843	0.02144
CARD6	5p13.1	Caspase recruitment domain family member 6	ENSG00000132357	0.0488
CLCNKA	1p36.13	Chloride voltage-gated channel Ka	ENSG00000186510	0.03672
CENPF	1q41	Centromere protein F	ENSG00000117724	0.01131