Research Article

Network Pharmacological Analysis and Experimental Study of the Antipharyngitis Mechanism of the Chaiqin Qingning Capsule

Table 2

The 54 potential antipharyngitis target genes of active ingredients.

UniProt IDProtein nameGene name

P08254Stromelysin-1MMP3
P27338Amine oxidase [flavin-containing] BMAOB
P05177Cytochrome P450 1A2CYP1A2
Q9Y2R2Tyrosine-protein phosphatase non-receptor type 22PTPN22
P09488Glutathione S-transferase Mu 1GSTM1
P22301Interleukin-10IL10
Q08209Serine/threonine-protein phosphatase 2B catalytic subunit alpha isoformPPP3CA
P00533Epidermal growth factor receptorEGFR
P00441Superoxide dismutase [Cu-Zn]SOD1
P21397Amine oxidase [flavin-containing] AMAOA
P60568Interleukin-2IL2
P04626Receptor tyrosine-protein kinase erbB-2ERBB2
P12830Cadherin-1CDH1
P38484Interferon gammaIFNG
P10415Apoptosis regulator Bcl-2BCL2
P08913Alpha-2A adrenergic receptorADRA2A
P05362Intercellular adhesion molecule 1ICAM1
P04798Cytochrome P450 1A1CYP1A1
Q14790Caspase-8CASP8
Q9NWT6Hypoxia-inducible factor 1-alphaHIF1A
P10145Interleukin-8CXCL8
P16581E-selectinSELE
P06401Progesterone receptorPGR
O95863Zinc finger protein SNAI1SNAI1
P04637ETS domain-containing protein Elk-1TP53
P08588Beta-1 adrenergic receptorADRB1
P01375Tumor necrosis factorTNF
P55211Caspase-9CASP9
P14778Interleukin-1 alphaIL1A
P38936Cyclin-dependent kinase inhibitor 1CDKN1A
P05164MyeloperoxidaseMPO
P31749RAC-alpha serine/threonine-protein kinaseAKT1
P40763Signal transducer and activator of transcription 3STAT3
P13866Sodium/glucose cotransporter 1SLC5A1
P35354Prostaglandin G/H synthase 2PTGS2
P00326Alcohol dehydrogenase 1CADH1C
P01584Interleukin-1 betaIL-1β
P24385G1/S-specific cyclin-D1CCND1
P47869Gamma-aminobutyric acid receptor subunit alpha-2GABRA2
P13726Tissue factorF3
P282235-hydroxytryptamine 2A receptorHTR2A
P07550Beta-2 adrenergic receptorADRB2
P15692Vascular endothelial growth factor AVEGFA
P01106Myc proto-oncogene proteinMYC
P20248Cyclin-A2CCNA2
P22303AcetylcholinesteraseACHE
P29965CD40 ligandCD40LG
P42224Signal transducer and activator of transcription 1-alpha/betaSTAT1
Q9NS23Ras association domain-containing protein 1RASSF1
P08684Cytochrome P450 3A4CYP3A4
P05231Interleukin-6IL-6
Q15722Leukotriene B4 receptor 1LTB4R
P42574Caspase-3CASP3
P14780Matrix metalloproteinase-9MMP9