Prognostic Nomogram for Gastrointestinal Stromal Tumors after Surgery Based on the SEER Database

Table 3

Performance of the derived nomogram and M-NIH classification in patients with GISTs.

Index	Training cohort			Validation cohort
	Estimate	95% CI	value	Estimate	95% CI	value
NRI (vs. M-NIH classification)
3-year GSS	0.346	0.198-0.472		0.356	0.171-0.551
5-year GSS	0.265	0.157-0.405		0.246	0.087-0.491
IDI (vs. M-NIH classification)
3-year GSS	0.047	0.031-0.083	<0.001	0.071	0.032-0.122	<0.001
5-year GSS	0.060	0.041-0.099	<0.001	0.084	0.040-0.142	<0.001
C-index
Nomogram	0.766	0.737-0.794		0.795	0.754-0.836
M-NIH classification	0.714	0.681-0.747		0.732	0.687-0.778
Change	0.051	0.020-0.073	<0.001	0.063	0.026-0.090	<0.001

C-index: concordance index; CI: confidence interval; GISTs: gastrointestinal stromal tumors; IDI: integrated discrimination improvement; M-NIH classification: modified NIH classification; NRI: net reclassification improvement.