Fuzheng Jiedu Decoction Induces Apoptosis and Enhances Cisplatin Efficacy in Ovarian Cancer Cells In Vitro and In Vivo through Inhibiting the PI3K/AKT/mTOR/NF-κB Signaling Pathway

Figure 8

Inhibitory effect of cisplatin on the cell growth, invasion, and apoptosis of SKOV-3 and 3AO cells and FJD enhancing the efficacy of cisplatin: (a) the cell viability of SKOV-3 and 3AO cells; (b) EdU assessed cell proliferation toxicity; (c) the changes of cell invasion ability; (d) the cell apoptosis was detected by the Annexin V-FITC/PI staining with flow cytometry; (e) the mitochondrial transmembrane potential was detected by the JC-1 staining with flow cytometry. Data was expressed as . Compared with the control group, ^▲, ^▲▲; compared with the Cis group, ^#, ^##; compared with the Cis+FJD-H group, ^%, ^%%.

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