BioMed Research International

Research Article

Molecular Mechanism of Gleditsiae Spina for the Treatment of High-Grade Serous Ovarian Cancer Based on Network Pharmacology and Pharmacological Experiments

Table 1

UPLC-MS/MS analysis results of the main chemical components of Gleditsiae Spina.


Peak number	tR/min	Molecular formula	Accurate	Calculated	Error (ppm)	Identified compounds

1.	0.824	C₆H₁₂O₆	180.06339	180.0629	−2.48	D-(+)-Glucose
2.	1.018	C₄H₆O₅	134.02152	134.0211	−2.92	DL-malic acid
3.	1.229	C₆H₆O₃	126.03169	126.0312	−4	Pyrogallol
4.	2.201	C₉H₁₇NO₅	219.11067	219.1102	−2.14	Pantothenic acid
5.	3.265	C₈H₈O₃	152.04734	152.047	−2.3	2-Anisic acid
6.	4.062	C₇H₆O₃	138.03169	138.0313	−3.07	Salicylic acid
7.	5.626	C₁₅H₁₄O₆	290.07904	290.0787	−1.33	Catechin
8.	5.72	C₆H₁₀O₄	146.05791	146.0576	−2.4	Adipic acid
9.	5.763	C₈H₈O₄	168.04226	168.0419	−2.36	Vanillic acid
10.	6.578	C₇H₆O₂	122.03678	122.0365	−2.45	Benzoic acid
11.	8.569	C₈H₈O₃	152.04734	152.047	−2.15	Vanillin
12.	9.315	C₁₀H₁₀O₄	194.05791	194.0575	−2.29	Ferulic acid
13.	10.946	C₁₅H₁₂O₇	304.0583	304.0576	−2.21	Dihydrorobinetin
14.	10.953	C₆H₆O₃	126.03169	126.0309	−5.95	Phloroglucinol
15.	4.049	C₁₁H₁₂N₂O₂	204.08988	204.0894	−2.25	D-(+)-Tryptophan
16.	11.22	C₂₁H₂₀O₁₀	432.10565	432.1049	−1.85	Isovitexin
17.	11.275	C₂₁H₂₀O₁₂	464.09548	464.0949	−1.25	Quercetin-3-O-glucoside
18.	12.071	C₉H₈O₂	148.05243	148.0521	−2.07	trans-Cinnamic acid
19.	12.774	C₂₁H₂₀O₁₁	448.10056	448.0998	−1.67	Isoorientin
20.	12.895	C₁₅H₁₂O₆	288.06339	288.0629	−1.64	Fustin
21.	13.052	C₉H₁₀O₂	150.06808	150.0678	−2.18	Hydrocinnamic acid
22.	15.655	C₈H₁₁NO	137.08406	137.0837	−2.6	Tyramine
23.	15.736	C₁₅H₁₀O₇	302.04265	302.042	−2.3	Robinetin
24.	15.751	C₁₅H₁₀O₆	286.04774	286.0472	−2.06	Luteolin
25	17.106	C₉H₁₆O₄	188.10486	188.1044	−2.64	Azelaic acid
26.	17.631	C₁₅H₁₀O₅	270.05282	270.0525	−1.36	Genistein
27.	21.755	C₁₆H₃₀O₄	286.21441	286.2139	−1.63	Hexadecanedioic acid
28.	38.385	C₃₀H₄₆O₄	470.33961	470.3389	−1.43	18-β-Glycyrrhetinic acid
29.	40.138	C₃₀H₄₈O₃	456.36035	456.3597	−1.36	Ursolic acid
30.	41.117	C₃₀H₄₈O₃	456.36035	456.36	−0.83	Oleanolic acid
31.	0.753	C₆H₁₄N₄O₂	174.11168	174.11157	−0.58	L-(+)-Arginine
32.	1.118	C₉H₁₁NO₃	181.07389	181.07368	−1.17	L-tyrosine
33.	9.58	C₁₀H₁₀O₂	162.06808	162.0679	−1.1	Methyl cinnamate
34.	11.63	C₉H₇NO	145.05276	145.05256	−1.41	8-Hydroxyquinoline
35.	11.787	C₂₁H₂₀O₁₀	432.10565	432.10494	−1.64	Vitexin
36.	13.668	C₁₀H₁₆O	152.12012	152.12	−0.75	Citral
37.	16.6	C₂₀H₁₇NO₄	335.11576	335.11495	−2.42	Berberine
38.	17.966	C₁₆H₁₂O₇	316.0583	316.05771	−1.89	Rhamnetin
39.	43.089	C₂₉H₄₈O₂	428.36543	428.36437	−2.48	Stigmastane-3,6-dione