Research Article

Determination of Risk Factors Associated with the Failure of 12 Weeks of Direct-Acting Antiviral Therapy in Patients with Hepatitis C: A Prospective Study

Table 3

Comparison of clinical models based on six machine learning classifiers in predicting therapeutic failure among patients with HCV.

ModelNo of variablesAUCROC95% CI (Delong)Pseudo 2BIC_value (>chi)

Model 1170.9790.961-0.9970.89114
Model 2160.9820.965-0.9980.88110.60.18224
Model 3150.9820.965-0.9970.86109.20.05621
Model 4130.980.962-0.9960.84102.20.19101
Model 5120.9840.968-0.9980.82101.10.04548
Model 6110.9860.971-0.9990.8101.10.02378

AUCROC: area under the receiver operating characteristic curve; BIC: Bayesian Information Criterion.