Rosiglitazone Protects against Acetaminophen-Induced Acute Liver Injury by Inhibiting Multiple Endoplasmic Reticulum Stress Pathways

<div>Rosiglitazone pretreatment suppressed APAP-induced activation of NF-<i>κ</i>B and PI3K/AKT pathways. (a) Representative immunoblots of NF-<i>κ</i>B (upper panel) and LaminA/C (lower panel). (b) Densitometry of NF-<i>κ</i>B showing upregulation by APAP and reversal by RSG pretreatment. (c) Representative immunoblots of p-AKT (upper panel) and AKT (lower panel). (d) Densitometry of p-AKT showing upregulation by APAP and reversal by RSG pretreatment. 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BioMed Research International

fig7

Figure 7

Figure 7: Rosiglitazone Protects against Acetaminophen-Induced Acute Liver Injury by Inhibiting Multiple Endoplasmic Reticulum Stress Pathways 