Anti-CD44 and EGFR Dual-Targeted Solid Lipid Nanoparticles for Delivery of Doxorubicin to Triple-Negative Breast Cancer Cell Line: Preparation, Statistical Optimization, and In Vitro Characterization

Figure 3

Response 3D plots for alteration in size of nanoparticles. The size of nanoparticles increased slightly by increasing the concentration ratio of GMS/lecithin from 0.5% () to 2% (). On the other hand, by increasing the concentration of Tween 80 from 1% () to 4% (), nanoparticles’ size declined linearly.