Anti-CD44 and EGFR Dual-Targeted Solid Lipid Nanoparticles for Delivery of Doxorubicin to Triple-Negative Breast Cancer Cell Line: Preparation, Statistical Optimization, and <i>In Vitro</i> Characterization

<div>Response 3D plots for alteration in polydispersity index of the nanoparticles. In the lowest concentration ratio of GMS/lecithin (i.e., 0.5), by increasing the concentration of Tween 80, the PDI values of the nanoparticles sharply declined. However, in the highest concentration of GMS/lecithin (i.e., 2.0), a slight decrease in PDI values was observed due to a rise in the concentration of Tween 80.</div>

BioMed Research International

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Figure 4

Figure 4: Anti-CD44 and EGFR Dual-Targeted Solid Lipid Nanoparticles for Delivery of Doxorubicin to Triple-Negative Breast Cancer Cell Line: Preparation, Statistical Optimization, and <i>In Vitro</i> Characterization 

Figure 4 | Anti-CD44 and EGFR Dual-Targeted Solid Lipid Nanoparticles for Delivery of Doxorubicin to Triple-Negative Breast Cancer Cell Line: Preparation, Statistical Optimization, and In Vitro Characterization 