Research Article

Serum Concentrations of Cartilage Intermediate Layer Protein 2 Were Higher in Overweight and Obese Subjects

Table 1

Comparison of clinical parameters in normal weight, overweight and obese subjects.

Clinical parametersNormal weight ()Overweight ()Obese ()

Age (years)0.679
Male (%)33.942.535.30.408
Diabetes (%)31.436.241.20.523
Body weight (kg)<0.001
Waist circumference (cm)<0.001
WHR<0.001
BMI (kg/m2)<0.001
FAT (%)28.65 (23.60-32.10)34.45 (25.70-37.00)41.05 (31.28-42.65)<0.001
SBP (mmHg)<0.001
DBP (mmHg)0.014
FBG (mmol/L)5.53 (5.00-6.36)5.78 (5.28-7.12)6.41 (5.21-7.34)0.041
2h-BG (mmol/L)8.65 (6.90-12.20)9.38 (7.10-12.38)9.92 (7.54-13.25)0.351
FIns (mu/L)6.58 (5.12-9.22)8.80 (5.88-12.43)12.73 (8.82-19.41)<0.001
HbA1c (%)5.90 (5.50-6.40)6.10 (5.70-6.80)6.30 (5.70-6.95)0.086
TG (mmol/L)1.22 (0.88-1.80)1.47 (1.08-2.16)1.80 (1.19-2.66)0.001
TC (mmol/L)0.556
HDL-C (mmol/L)0.006
LDL-C (mmol/L)0.339
FFA (μmol/L)0.933
HOMA-IR1.74 (1.25-2.78)2.39 (1.50-4.01)3.88 (2.54-5.61)<0.001

Values are given as or median (interquartile range). WHR: waist-to-hip ratio; BMI: body mass index; SBP: systolic blood pressure; DBP: diastolic blood pressure; FBG: fasting blood glucose; 2h-BG: 2-hour OGTT blood glucose; FIns: fasting blood insulin; TG: triglyceride; TC: total cholesterol; LDL-C: low-density lipoprotein cholesterol; HDL-C: high-density lipoprotein cholesterol; FFA: free fatty acid; HOMA-IR: homeostasis model assessment of insulin resistance.