Development and Validation of a Nomogram for Predicting Overall Survival to Concurrent Chemoradiotherapy in Patients with Locally Advanced Esophageal Squamous Cell Carcinoma

Table 2

Multivariate Cox regression of the training set.

Variable		HR	HR 95% CI	value	value
Age	0.02	1.02	1.00-1.03	2.45	0.014
Location
Neck/upper	1 [reference]	1 [reference]	1 [reference]	—	—
Middle/lower	0.64	1.90	1.45-2.49	4.64	<0.001
N stage
N0	1 [reference]	1 [reference]	1 [reference]	—	—
N+	0.91	2.48	1.77-3.47	5.31	<0.001
Tumor response
CR	1 [reference]	1 [reference]	1 [reference]	—	—
PR	0.85	2.34	1.61-3.40	4.47	<0.001
SD/PD	1.82	6.14	3.47-10.89	6.22	<0.001
MLR (per 0.1 change)	0.21	1.24	1.15-1.34	5.38	<0.001

HR: hazard ratio; CI: confidence interval; MLR: monocyte/lymphocyte ratio; CR: complete response; PR: partial response; SD: stable disease; PD: progressive disease.