DIA-PRM Proteomic Analysis of Phlegm-Dampness Constitution with Glucolipid Metabolic Disorders by the Intervention of Hua Tan Qu Shi Recipe

Table 3

Overlapping pathways among the AW-W, AT-T, and AZ-Z groups.

Canonical pathways	-score
	AW-W	AT-T	AZ-Z
LXR/RXR activation	-1.291	3.8	4.271
FXR/RXR activation	N/A	N/A	N/A
Acute phase response signaling	-1	2.111	2.496
Production of nitric oxide and reactive oxygen species in macrophages	-1	2.887	3.051
Clathrin-mediated endocytosis signaling	N/A	N/A	N/A
Coagulation system	N/A	0	1.147
Complement system	0	1.134	1.265
Atherosclerosis signaling	N/A	N/A	N/A
IL-12 signaling and production in macrophages	N/A	N/A	N/A
Intrinsic prothrombin activation pathway	N/A	1.89	2.887
Extrinsic prothrombin activation pathway	N/A	0.447	0.447
Caveolar-mediated endocytosis signaling	N/A	N/A	N/A
Hepatic fibrosis signaling pathway	2	N/A	N/A
Glucocorticoid receptor signaling	N/A	N/A	N/A
GP6 signaling pathway	2	N/A	N/A
Integrin signaling	2.236	N/A	N/A
Leukocyte extravasation signaling	1	N/A	N/A
Neuroinflammation signaling pathway	N/A	N/A	N/A
Actin cytoskeleton signaling	2	N/A	0
Systemic lupus erythematosus signaling	N/A	N/A	N/A
Phagosome formation	2.121	1.89	2.449

Notes: N/A: not applicable; , activation; , inhibition.