Identifying miRNAs Associated with the Progression of Keloid through mRNA-miRNA Network Analysis and Validating the Targets of miR-29a-3p in Keloid Fibroblasts

Table 4

493 co-DEGs (318 co-up DEGs and 175 co-down DEGs).

Co-up DEGs (318)

PTN ST6GAL2 GREM1 F2RL2 ELN ARL4C TMEM200A FBLN7 TMEM176A KIF5C OAF CNPY4 TPBG TMEM176B PLAU LSAMP EDNRA GPR68 DNAH12 TDO2 ECM2 COL10A1 LAMP5 ADAMTS16 COL11A1 MFAP2 MDK ITGA10 GLIS3 THBS4 PAX1 ZNF469 PYCR1 GALNT5 TMEM92 RUNX2 PXDN AMPH MEG9 SULF2 NREP THY1 CADPS PCDH17 BGN DNM3OS CH25H TRO CASC15 GPX7 EPHB2 LINC01116 GLT8D2 CHPF COL8A1 CALU TRANK1 CSMD2 PDE1A DOK5 TTYH3 COL5A2 MS4A7 C2 FZD2 NID1 SUGCT BAG2 PRAF2 SLC41A2 ARHGEF25 PRDM6 MEG3 CLEC11A TPBGL CTHRC1 RFTN2 CALD1 THSD7A BICC1 EFEMP2 CHRD ARMC9 CRISPLD2 ADAMTS1 KHDRBS3 LAYN FIBIN ANTXR1 RRBP1 FBXL7 PPIC SH3RF3 SLC2A10 CREB3L1 NBL1 MX2 GPR4 TP53I3 NR2F1-AS1 ORAI2 C2orf27A SEMA6B MMP19 DZIP1 GRB10 THBS3 ATP8B3 DLG4 ATP10A LRRC15 MLLT11 GJA5 OAS2 SLC39A7 ZNF521 ZNF275 C11orf24 PDE7B BCL6B DPY19L3 SNHG18 MAGED1 NEK6 LPCAT1 SMARCA1 COL3A1 ENAH FAM229B NLGN2 PRSS23 ARPC1B LAMA2 SLFN11 COPZ2 CNTN4 DCLK2 SDK1 CTSK HTRA1 IGF2 TNFAIP6 THBS2 RYR2 PDGFRL TIMP1 TGFB1 ARHGAP28 ADAMTSL1 ARSB MSR1 DPP4 ITGBL1 ITGA4 TRAM2 MYO1B PODN TSHZ3 ST3GAL2 GFPT2 PDGFRB ADAMTS4 HIC1 TNC SCN1B SCARF2 RCN1 ADAM23 SLC36A1 HTRA3 PDIA5 CD276 IFI16 ADAMTS7 CYTL1 VOPP1 GLT8D1 CHST1 CARD6 PEAK1 SAMD9L P4HA3 SFRP4 CPXM1 SYNDIG1 COMP ADAM12 CILP2 COL14A1 OLFML2B ACAN ASPN SULF1 ADAMTS14 CDH11 GRIN2D PIEZO2 C1QTNF6 TNFSF4 PLAUR ADAMTS12 CHSY3 CGREF1 KDELR3 COL12A1 TMEM119 ALPK2 FKBP10 MMP14 FNDC1 LRRC17 SERPINH1 FAP VCAN HEY2 SGCD SORCS2 TGFB3 COL6A1 CERCAM MMP16 GXYLT2 RCN3 SPON1 NOX4 UCHL1 PCOLCE C1S ZFHX4 ROR2 COL5A1 NID2 ADAMTS6 POSTN KCNMA1 SFRP2 NNMT HMCN1 OGN IGDCC4 CHN1 ANGPTL2 GEM RHOBTB1 FMNL3 SSC5D COL1A1 NPTX2 SEC24D ISG15 FKBP14 GPX8 SEMA3A DACT1 ADAM19 RAB31 IKBIP SH3PXD2B FN1 ADAMTS2 COL6A2 PAPSS2 EDIL3 CHST11 PRR16 NRP2 LUM RNF144A BMP1 BEND6 SATB2 PLXDC1 GUCY1A2 FKBP7 MN1 MXRA8 SHOX2 NR2F1 FBN1 BNC2 LAMB1 CMTM3 HAPLN3 NRP1 PRRX1 AEBP1 OMD MARCKS NAV1 MAP4K4 COL16A1 OLFML3 SEC23A KCNE4 FKBP11 LOX MRC2 ALDH1L2 LRRC32 COL1A2 DCHS1 BCAT1 EPHA3 BASP1 RHOJ COL6A3 IL1R1 EVI2A ATP8B2 L3MBTL3 LOXL2 PGM3 SYTL2 STEAP1 TPST1 PRR5L FUCA2 MXRA5

Co-down DEGs (175)

VSIG10L SH3BGRL2 MATN4 HSD11B2 SCNN1G SLC14A1 KRT75 RHCG CHDH PLAG1 SPDEF MYBPC1 TMEM61 ESRRG EML2 KLK1 SUSD2 TRNP1 OCLN TPD52L1 SPIRE2 TBX3 FBXO32 ACSS2 SLC25A4 ADAMTSL3 SLC46A2 SYNGR1 CYP39A1 GLDN RRAGD USP54 ECHDC3 CHCHD10 COBL SORT1 LNX1 GCNT2 KRT77 C1orf226 SLC29A2 CDH22 PNPLA3 NRG2 ME1 CLYBL TMOD1 KRTCAP3 NEDD4L TMEM125 TST PLEKHG6 RASD1 GPRC5C CEACAM1 NNAT EPB41L4B SLC4A11 LIPH REEP6 CYP4X1 DNAH17 RNF128 ZG16B RAB3B CLDN8 RASSF10 SLC13A2 PLIN5 BEX2 CCL28 DLX4 DHCR7 KIAA0895 FOXC1 CHI3L1 JPH2 PAMR1 GPD1 SGCG HSD11B1 STK32A KCNQ4 SOX9 SAPCD2 HMGCS2 FAM189A2 MSMB RASD2 GPR12 CDA STAC2 ABTB2 SYNM MUCL1 CYP4F8 TNNI2 KCNMB1 SLC12A2 MGST1 BAMBI MAL ATP13A5 PADI2 ATP6V1B1 PPARGC1A KCNN4 CEACAM5 CLDN7 MYEOV PPP1R1A SHANK2 ELF3 KRT7 EPCAM ANXA3 KLRG2 G0S2 EDAR RHPN2 CNN1 CIDEC MMP7 GAL KRT18 YBX2 FA2H PRR15L PPP1R1B GABRP KRT19 ACTG2 THRSP TSPAN8 CEACAM6 PLIN4 SPRR4 CA6 KRT79 PLIN1 CLDN10 DNER SCGB2A2 ADIPOQ DCD SCGB1D2 PIP PRRG2 SRCIN1 HOXC13 TOB1 CADM4 FANCE CPEB3 PDCD4 GCHFR TFAP2B ATP1A1 PFKFB3 SLC25A23 EEF1A2 PANK1 RAP1GAP CHRM1 ELF5 SLC2A4 NCALD SH3D21 TMPRSS2 FMO5 ATP1B1 S100A1 KCNK5 AQP5 ATP6V0A4