Research Article

Plasma Methylated RNF180 for Noninvasive Diagnosis of Gastric Cancer

Table 2

Sensitivity, specificity, PPV, and NPV of mRNF180 and serum tumor markers.

Sensitivity (95% CI)Specificity (95% CI)PPV (95% CI)NPV (95% CI)

mRNF18071.67 (58.36-82.18)59.38 (48.85-69.14)52.44 (41.18-63.47)77.03 (65.52-85.68)
CEA28.33 (17.82-41.64)95.83 (89.07-98.66)80.95 (57.42-93.71)68.15 (59.50-75.75)
CA19926.67 (16.45-39.89)92.71 (85.06-96.77)69.57 (46.99-85.94)66.92 (58.16-74.68)
CA72428.33 (17.82-41.64)88.54 (80.02-93.86)60.71 (40.73-77.87)66.41 (57.45-74.36)

PPV: positive predictive value; NPV: negative predictive value.