Plasma Methylated RNF180 for Noninvasive Diagnosis of Gastric Cancer

Table 5

Correlations between mRNF180 and clinicopathological characteristics of the GC group.

Clinicopathological characteristics	mRNF180
		Positive	Negative		Mean ΔCt value
Sex				1.000		0.746
Male	44	31	13		8.22
Female	16	12	4		7.88
Age (years)				0.171		0.010
<70	34	22	12		9.15
≥70	26	21	5		6.80
Tumor location
Upper third	16	11	5		NA
Middle third	20	14	6		NA
Lower third	18	12	6		NA
>2/3 stomach	4	4	0		NA
NA	2
Tumor size (cm)				0.142		0.033
<6.0	25	16	9		9.09
≥6.0	32	26	6		7.08
NA	3	1	2
T stage				0.005		0.004
Tis+T1+T2+T3	20	10	10		9.78
T4	34	29	5		6.94
NA	6	4	2
N stage				0.001		≦0.001
N0+N1	23	11	12		10.28
N2+N3	30	27	3		6.27
NA	7	5	2
M stage				0.463		0.011
M0	38	26	12		9.01
M1	22	17	5		6.61
NA	0
Clinical stage				0.051		0.022
0+I+II	11	5	6		10.15
III+IV	45	36	9		7.44
NA	4	2	2
Differentiation				0.284		0.057
High+moderate	12	6	6		10.18
Low	32	23	9		7.73
NA	16	14	2