Serum LAPTM4B as a Potential Diagnostic and Prognostic Biomarker for Breast Cancer

Table 3

Correlation of serum LAPTM4B with clinical indicators in breast cancer patients (median (IQR)).

Variables	Number	LAPTM4B (ng/mL)	value
Age
≤ 55	226	9.31 (14.68)	0.020
> 55	200	11.14 (31.12)
Menopausal status
Premenopausal	211	9.76 (15.39)	0.206
Postmenopausal	215	10.53 (28.36)
Hypertension
-ve	116	9.78 (19.83)	0.302
+ve	310	12.55 (30.15)
Diabetes
-ve	386	10.73 (24.75)	0.192
+ve	40	7.21 (15.92)
Histological type
IDC	328	10.77 (27.63)	0.021
Others	98	8.25 (14.75)
TNM stage
I + II	250	8.85 (15.40)	0.001
III + IV	176	13.91 (35.33)
Tumor size
≥ 20 mm	208	10.59 (28.08)	0.694
< 20 mm	218	9.78 (20.91)
Nodal status
-ve	237	8.49 (15.46)	<0.001
+ve	189	13.84 (35.57)
Distant metastasis status
-ve	277	9.00 (18.25)	0.001
+ve	149	15.16 (34.98)
Recurrence
-ve	301	8.59 (14.77)	<0.001
+ve	125	16.70 (34.78)
ER
-ve	97	15.97 (38.98)	<0.001
+ve	329	9.00 (16.03)
PR
-ve	134	13.91 (35.59)	0.003
+ve	292	8.99 (18.18)
HER2
-ve	115	11.38 (21.58)	0.996
+ve	311	9.76 (24.79)
Ki-67
-ve	52	7.12 (11.09)	0.034
+ve	374	10.66 (27.55)
Triple-negative
Yes	19	25.68 (60.32)	0.006
No	407	9.51 (21.83)