Research Article
[Retracted] Magnetic Resonance Neuroimaging Contrast Agents of Nanomaterials
Table 2
Organic macromolecules and their advantages of functionalized iron oxide NPs.
| Types of polymers | Polymers | Characteristics |
| Natural polymers | Dextran | Enables optimum polar interactions with iron oxide surfaces, improves the blood circulation time, stability, and biocompatibility | Chitosan | Nontoxic, alkaline, hydrophilic, widely used as nonviral gene delivery system, biocompatible, and hydrophilic | Starch | Improves the biocompatibility, good for MRI and drug target delivery | Gelatin | Used as a gelling agent, hydrophilic emulsifier, biocompatible |
| Synthetic polymers | Polyethylene glycol (PEG) | Enhances the hydrophilicity and water solubility, improves the biocompatibility, blood circulation times | Polyvinyl alcohol (PVA) | Prevents agglomeration, giving rise to monodispersibility | Polymethyl methacrylate (PMMA) | Generally used as thermosensitive drug delivery and cell separation | Polyacrylic acid (PAA) | Improves stability and biocompatibility as well as bioconjugation |
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