Research Article

[Retracted] Magnetic Resonance Neuroimaging Contrast Agents of Nanomaterials

Table 2

Organic macromolecules and their advantages of functionalized iron oxide NPs.

Types of polymersPolymersCharacteristics

Natural polymersDextranEnables optimum polar interactions with iron oxide surfaces, improves the blood circulation time, stability, and biocompatibility
ChitosanNontoxic, alkaline, hydrophilic, widely used as nonviral gene delivery system, biocompatible, and hydrophilic
StarchImproves the biocompatibility, good for MRI and drug target delivery
GelatinUsed as a gelling agent, hydrophilic emulsifier, biocompatible

Synthetic polymersPolyethylene glycol (PEG)Enhances the hydrophilicity and water solubility, improves the biocompatibility, blood circulation times
Polyvinyl alcohol (PVA)Prevents agglomeration, giving rise to monodispersibility
Polymethyl methacrylate (PMMA)Generally used as thermosensitive drug delivery and cell separation
Polyacrylic acid (PAA)Improves stability and biocompatibility as well as bioconjugation