The Protective Effects of Securigera securidaca Seed Extract on Liver Injury Induced by Bile Duct Ligation in Rats

Figure 3

Effects of Securigera securidaca seed extract on the histopathological changes of the liver in BDL-afflicted rats. Representative photomicrographs of liver sections processed for H and E staining (10; scale bar 5 mm). (a) Sham X100; (b) BDL-control X100; (c) BDL-control X400; (d) BDL+VitCX100; (e) BDL+SS100 X100; and (f) BDL+SS200 X100. (a) Represents the normal liver histopathology. (b, c) Fibrosis (white arrow) and bile duct hyperplasia (red arrow) in addition to extensive tissue necrosis (green arrow) and inflammation (yellow arrow) are evident in rats with untreated BDL as shown in (b) and (c). In (d) and (c), bile duct hyperplasia is indicated by red arrow, and fibrosis is marked by white arrow. All these lesions markedly decreased in rats treated with 100 mg/kg SS seed extract.

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