[Retracted] Brusatol Inhibits Proliferation and Metastasis of Colorectal Cancer by Targeting and Reversing the RhoA/ROCK1 Pathway

Figure 5

Possible mechanism of BRU reversal of EMT process in colorectal cancer cells. After HCT-116 and SW480 cells were treated with or without BRU, Y27632 and BRU + Y27632, RhoA and ROCK1 in cells were analyzed by western blot (a, c) and quantitative analysis by the Image Lab software (b, d); after HCT-116 and SW480 cells were treated with or without BRU, Y27632, BRU + Y27632, western blot analysis of E-cadherin, Vimentin, N-cadherin, MMP2, MMP9 in cells (e, g) and quantitative analysis of the Image Lab software (f, h). All data were shown as from three independent trials (, vs. control).

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