Research Article
A Three-mRNA Signature Associated with Pyrimidine Metabolism for Prognosis of BRCA
Table 4
The relation between risk score and clinical features.
| | Clinical feature | Risk score | | | | High risk (%) | Low risk (%) |
| | Age | | | 0.044 | 0.835 | | ≥58 | 285 (26.27) | 280 (25.81) | | | | <58 | 259 (23.87) | 261 (24.05) | | | | T | | | 8.930 | 0.030 | | T1 | 126 (11.65) | 153 (14.14) | | | | T2 | 333 (30.78) | 294 (27.17) | | | | T3 | 59 (5.45) | 78 (7.21) | | | | T4 | 23 (2.13) | 16 (1.47) | | | | N | | | 10.250 | 0.017 | | N0 | 250 (23.47) | 296 (27.79) | | | | N1 | 171 (16.06) | 152 (14.27) | | | | N2 | 72 (6.76) | 47 (4.41) | | | | N3 | 38 (3.57) | 39 (3.67) | | | | M | | | 0.003 | 0.960 | | M0 | 478 (51.73) | 425 (46.00) | | | | M1 | 11 (1.19) | 10 (1.08) | | | | Stage | | | 5.344 | 0.148 | | I | 77 (7.25) | 104 (9.79) | | | | II | 309 (29.10) | 307 (28.91) | | | | III | 132 (12.43) | 114 (10.73) | | | | IV | 9 (0.85) | 10 (0.94) | | | | Person neoplasm cancer status | | | 3.477 | 0.062 | | Tumor-free | 420 (43.66) | 448 (48.38) | | | | With tumor | 55 (5.94) | 39 (2.02) | | | | PR status by IHC | | | 3.266 | 0.071 | | Negative | 184 (17.83) | 158 (15.31) | | | | Positive | 330 (31.98) | 360 (34.88) | | | | ER status by IHC | | | 8.363 | 0.004 | | Negative | 138 (13.33) | 100 (9.66) | | | | Positive | 377 (36.43) | 420 (59.90) | | | | HER-2 status by IHC | | | 1.049 | 0.306 | | Negative | 283 (39.42) | 274 (38.16) | | | | Positive | 86 (11.98) | 75 (10.44) | | |
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