MRGBP: A New Factor for Diagnosis and Prediction of Head and Neck Squamous Cell Carcinoma

Table 3

Associations with clinicopathological characteristics in HNSC patients using Cox regression.

Characteristics	Total ()	Univariate analysis		Multivariate analysis
		Hazard ratio (95% CI)	value	Hazard ratio (95% CI)	value
Age	501
≤60	245	Reference
>60	256	1.252 (0.956-1.639)	0.102
Race	485
Asian and Black or African American	57	Reference
White	428	0.680 (0.450-1.028)	0.067	0.843 (0.537-1.322)	0.456
Smoker	491
No	111	Reference
Yes	380	1.089 (0.778-1.525)	0.618
Clinical stage	487
Stage I and stage II	113	Reference
Stage III and stage IV	374	1.217 (0.878-1.688)	0.238
T stage	486
T1 and T2	176	Reference
T3 and T4	310	1.245 (0.932-1.661)	0.137
N stage	479
N0 and N1	318	Reference
N2 and N3	161	1.384 (1.040-1.842)	0.026	1.308 (0.972-1.759)	0.076
M stage	476
M0	471	Reference
M1	5	4.745 (1.748-12.883)	0.002	4.014 (1.411-11.419)	0.009
MRGBP	501	1.301 (1.052-1.608)	0.015	1.332 (1.064-1.668)	0.012