Systematic Construction and Validation of an Immune-Related Gene-Based Model to Predict Prognosis for Ovarian Cancer

Figure 5

Identification of differentially expressed TFs for ovarian cancer. Heatmap (a) and a volcano plot (b) show distinctly expressed TFs between ovarian cancer tissues and normal tissues. The color in the heatmap from green to red represents the progression from low expression to high. The areas below the blue band represent normal samples, and the areas below the red band represent tumor samples. Colored dots in the volcano map represent differentially expressed TFs. Red on behalf of higher expression while green means lower expression in OC.(c) 4 important TFs involved in immune regulation and prognosis of OC: Transcription factors are represented by triangles; high-risk immune genes are represented by deep pink; low-risk immune genes are represented by pale pink; the positive regulation relationship is denoted by red connection. The negative control relationship is connected with the green line.

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