Research Article
[Retracted] Fluoride Exposure Suppresses Proliferation and Enhances Endoplasmic Reticulum Stress and Apoptosis Pathways in Hepatocytes by Downregulating Sirtuin-1
Figure 2
Effects of fluoride exposure on Sirt-1, ERS, and apoptosis pathways in rats. 10 and 50 mg/L NaF were applied to feed the Wistar rats. (a, b) RT-qPCR analysis of Sirt-1 and PERK expressions in liver tissues. (c) Western blot demonstrated the changes in PERK, Sirt-1, GRP-78, ATF6, CHOP, and caspase-3 expressions in liver tissues. (d) Quantitative analysis of the above Western blot results. , .
(a) |
(b) |
(c) |
(d) |