Prognostic Value of GIMAP4 and Its Role in Promoting Immune Cell Infiltration into Tumor Microenvironment of Lung Adenocarcinoma

Figure 7

Mutation landscape of LUAD across different expression of GIMAP4. (a) Lollipop plot displaying mutation distribution and protein domains for GIMAP4 in cancer with labeled recurrent hotspots. Somatic mutation rate and transcript names are indicated by plot title and subtitle. (b) Oncoplot displaying the somatic landscape of LUAD cohort. Genes are ordered by their mutation frequency, and samples are ordered by GIMAP4 expression as indicated by the annotation bar. Side bar plot shows log10 transferred -values estimated by MutSigCV. Mutation information of each gene in each sample was shown in the waterfall plot, where different colors with specific annotations (bottom) meant the various mutation types. The bar plot above exhibited the number of mutation burden. (c) Cohort summary plot displays distribution of variants based on variant classification, type, and SNV class. Plots at the bottom (from left to the right) indicate mutation load per sample, variant classification type, and ten mutated genes.

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