Screening Potential Diagnostic Biomarkers for Age-Related Sarcopenia in the Elderly Population by WGCNA and LASSO

Table 3

Evaluation of hub gene diagnostic capabilities.

Gene symbol	Sensitivity (%)	Specificity (%)	AUC	95% CI	Youden index
FAM171A1	0.837	0.94	0.929	0.874-0.985	0.777
ZNF415	1	0.66	0.925	0.875-0.974	0.66
MT1X	0.93	0.84	0.932	0.880-0.983	0.77
C6orf136	0.767	0.82	0.83	0.743-0.917	0.587
GPCPD1	0.86	0.84	0.912	0.856-0.968	0.7
RXRG	0.907	0.76	0.92	0.868-0.972	0.667
ARHGAP36	0.791	0.96	0.91	0.851-0.969	0.751
SCN4B	0.814	0.8	0.865	0.793-0.938	0.614
HOXB2	0.837	0.9	0.888	0.812-0.964	0.737
ATP1B4	0.86	0.76	0.87	0.796-0.943	0.62
NEDD1	0.721	0.86	0.833	0.750-0.917	0.581
TGFBR3	0.814	0.72	0.833	0.749-0.918	0.534
MT2A	0.814	0.68	0.799	0.711-0.888	0.494
KLF5	0.791	0.8	0.847	0.765-0.928	0.591
TXNIP	0.674	0.68	0.712	0.608-0.816	0.354