hsa-miR-206b Involves in the Development of Papillary Thyroid Carcinoma via Targeting LMX1B

Figure 2

The differentially expressed miRNAs with prognostic implications for all 493 PTC patients from TCGA-THCA data collection. (a) Kaplan-Meier survival analysis of differentially expressed miRNAs (filtering criteria: and ), of which 5 miRNAs (hsa-miR-206, hsa-miR-299-3p, hsa-miR-299-5p, hsa-miR-496, and hsa-miR-509-3-5p) were statistically significant (). We calculated the hazard ratios (HR) and values with a univariate Cox regression analysis and the log-rank test. OS: overall survival. (b) The expression levels of the five miRNAs (hsa-miR-206, hsa-miR-299-3p, hsa-miR-299-5p, hsa-miR-496, and hsa-miR-509-3-5p) between the 165 stage III_IV patients and the 328 stage I_II patients. values were calculated by the Wilcoxon rank sum test.

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