Research Article

hsa-miR-206b Involves in the Development of Papillary Thyroid Carcinoma via Targeting LMX1B

Table 1

Clinical characteristics of 493 PTC patients from TCGA-THCA database, stratified by disease stages (stage I_II vs. stage III_IV).

CharacteristicsTotalStage I_IIStage III_IV value

No.493328165
Gender (%)
 Female360 (73.02)249 (75.91)111 (67.27)0.0533
 Male133 (26.98)79 (24.09)54 (32.73)
Age (%)
 <60382 (77.48)284 (86.59)98 (59.39)<0.0001
 >60111 (22.52)44 (13.41)67 (40.61)
Radiation therapy (%)
 No178 (36.10)143 (43.60)35 (21.21)<0.0001
 Yes315 (63.89)185 (56.40)130 (78.79)
Neoadjuvant therapy (%)
 No489 (99.19)326 (99.39)163 (98.79)0.8638
 Yes4 (0.81)2 (0.61)2 (1.21)
Survival status (%)
 Alive477 (96.75)324 (98.78)153 (92.73)0.0009
 Dead16 (3.25)4 (1.22)12 (7.27)

Patients of stage I and stage II were categorized as the stage I_II group, and patients of stage III and IV were categorized as the stage III_IV group. value is derived from the univariate association analyses between each of the clinicopathologic variables and stage status. value < 0.05 and value < 0.001.