PTBP1 is a Novel Poor Prognostic Factor for Glioma

Table 3

Univariate and multivariate analyses for overall survivals.

Variable	Univariate analysis		Multivariate analysis
	Hazard ratio (95% CI)	value	Hazard ratio (95% CI)	value
Gender: male	1.231 (0.880~1.983)	0.179
Age: >55	2.116 (1.397~3.207)	<0.001	1.464 (0.950-2.257)	0.084
Location: supratentorial	0.546 (0.173~1.729)	0.304
WHO grade: WHO 4	1.845 (1.411~2.414)	<0.001	0.823 (0.558-1.213)	0.325
IDH: mutated	0.308 (0.191~0.494)	<0.001	0.613 (0.338-1.113)	0.108
KPS: >70	0.721 (0.488~1.066)	0.102
Ki67: >10%	2.225 (1.182~4.187)	0.013	1.624 (0.802-3.289)	0.178
PTBP1: high	5.807 (3.732~9.036)	<0.001	4.901 (2.778-8.645)	<0.001

.