IgA-Type Enterovirus Antibodies Are Increased among Adults and Children with Recently Diagnosed Type 1 Diabetes

Table 2

Prevalence of antibodies to enteroviruses (EV) in participants with type 1 diabetes (T1D) and controls.

Antibodies	Control		T1D		Matched OR
		% (95% CI)		% (95% CI)	(95% CI)	value
IgA EV	7/62	11.3 (5.0–22.5)	29/62	46.8 (34.2–59.8)	8.33 (2.52–27.6)	0.0005
IgG EV	29/62	46.8 (34.2–59.8)	30/62	48.4 (35.7–61.3)	1.07 (0.52–2.22)	0.8530
IgM EV	1/57	1.8 (0.09–10.6)	3/57	5.2 (1.4–15.5)	3.00 (0.31-28.8)	0.3410

Data are provided as the number of EV-positive persons and percentage with the 95% confidence interval (CI). Conditional logistic regression model: matched odds ratio for gender, age, and HLA-DR/DQ genotype risk groups for T1D with the 95% confidence interval (CI). values ≤ 0.05 are in bold.