Research Article
GRWR Correlates with the Metabolism of Tacrolimus after Pediatric Living Donor Liver Transplantation According to Donor CYP3A5 Polymorphism
Table 5
Comparison of TAC dose requirement among the 4 groups.
| Posttransplant time | TAC dose requirement (mg/kg/d) | SS/NEX group () | SS/EX group () | LS/NEX group () | LS/EX group () |
| 3 days | 0.11 (0.09-0.13) | 0.12 (0.11-0.16) | 0.14 (0.13-0.17) | 0.14 (0.12-0.15) | 7 days | 0.10 (0.06-0.13) | 0.12 (0.08-0.16) | 0.13 (0.08-0.17) | 0.18 (0.13-0.20) | 14 days | 0.13 (0.08-0.17) | 0.21 (0.12-0.26) | 0.17 (0.14-0.24) | 0.25 (0.18-0.28) | 1 month | 0.18 (0.10-0.23) | 0.22 (0.17-0.32) | 0.23 (0.19-0.27) | 0.25 (0.21-0.32) | 3 months | 0.14 (0.11-0.17) | 0.23 (0.18-0.28) | 0.18 (0.13-0.22) | 0.22 (0.20-0.24) | 6 months | 0.10 (0.07-0.12) | 0.18 (0.13-0.23) | 0.11 (0.07-0.14) | 0.16 (0.10-0.18) | 12 months | 0.07 (0.04-0.09) | 0.11 (0.08-0.16) | 0.05 (0.04-0.09) | 0.08 (0.04-0.12) |
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Note: Data are expressed as median (lower quartile-upper qurtile). indicates compared with the SS/NEX group; indicates compared with the SS/NEX group. |