Research Article

GRWR Correlates with the Metabolism of Tacrolimus after Pediatric Living Donor Liver Transplantation According to Donor CYP3A5 Polymorphism

Table 5

Comparison of TAC dose requirement among the 4 groups.

Posttransplant timeTAC dose requirement (mg/kg/d)
SS/NEX group ()SS/EX group ()LS/NEX group ()LS/EX group ()

3 days0.11 (0.09-0.13)0.12 (0.11-0.16)0.14 (0.13-0.17)0.14 (0.12-0.15)
7 days0.10 (0.06-0.13)0.12 (0.08-0.16)0.13 (0.08-0.17)0.18 (0.13-0.20)
14 days0.13 (0.08-0.17)0.21 (0.12-0.26)0.17 (0.14-0.24)0.25 (0.18-0.28)
1 month0.18 (0.10-0.23)0.22 (0.17-0.32)0.23 (0.19-0.27)0.25 (0.21-0.32)
3 months0.14 (0.11-0.17)0.23 (0.18-0.28)0.18 (0.13-0.22)0.22 (0.20-0.24)
6 months0.10 (0.07-0.12)0.18 (0.13-0.23)0.11 (0.07-0.14)0.16 (0.10-0.18)
12 months0.07 (0.04-0.09)0.11 (0.08-0.16)0.05 (0.04-0.09)0.08 (0.04-0.12)

Note: Data are expressed as median (lower quartile-upper qurtile). indicates compared with the SS/NEX group; indicates compared with the SS/NEX group.