Research Article

GRWR Correlates with the Metabolism of Tacrolimus after Pediatric Living Donor Liver Transplantation According to Donor CYP3A5 Polymorphism

Table 6

Comparison of TAC C/D ratio among the 4 groups.

Posttransplant timeTAC C/D ratio (ng/ml)/(mg/kg/d)
SS/NEX group ()SS/EX group ()LS/NEX group ()LS/EX group ()

3 days113.7 (99.2-150.0)62.5 (43.4-100.3)74.4 (59.9-100.0)51.5 (43.2-82.2)
7 days104.9 (70.2-192.0)75.3 (40.7-117.4)70.4 (57.2-102.4)41.1 (31.1-76.8)
14 days69.1 (51.8-132.4)31.6 (24.8-59.1)42.4 (33.6-58.0)28.1 (20.3-46.4)
1 month59.7 (33.8-89.2)31.7 (18.9-49.0)34.9 (25.6-50.8)20.5 (16.2-28.7)
3 months71.1 (53.4-91.8)30.3 (20.6-47.5)53.8 (42.5-68.7)27.3 (21.9-37.1)
6 months75.6 (60.8-103.7)34.0 (27.4-47.8)69.0 (46.0-95.1)41.3 (29.2-47.3)
12 months80.0 (57.3-92.8)42.0 (29.6-63.5)79.1 (56.0-136.0)49.5 (41.0-85.7)

Note: Data are expressed as median (lower quartile-upper qurtile). indicates compared with the SS/NEX group; indicates compared with the SS/NEX group.