Research Article

Single-Cell Gene Expression Analysis in Patients with Medullary Sponge Kidney and a Retrospective Study

Table 1

Clinical data of 17 patients with medullary sponge kidney.

No.AgeGenderPrimary diagnosisSecondary diagnosisSupplement

Patient 1Y49FemaleMedullary sponge kidney(1) Double renal calculi, (2) left upper ureteral calculi, (3) left uronephrosis, (4) renal insufficiency, (5) urinary infection, (6) hypokalemia, (7) hypoproteinemia, (8) anemia
Patient 2Y66MaleMedullary sponge kidney(1) Double renal calculi, (2) urethrostenosis, (3) renal insufficiency, (4) urinary infection, (5) hyperthyroidism, (6) metabolic acidosis, (7) hypertension, (8) anemia
Patient 3Y74MaleMedullary sponge kidney(1) Double renal calculi, (2) double renal cyst, (3) renal insufficiency, (4) ileus, (5) metabolic acidosis, (6) hyperkalemia, (7) hyponatremia, (8) hypochloremia, (9) anemia
Patient 4Y33FemaleMedullary sponge kidney(1) Double renal calculi, (2) G2P2 39 W +3 LOA, (3) single live birth–male, (4) type 2 diabetes, (5) hypokalemiaNeonatal hypospadias
Patient 5Y73FemaleMedullary sponge kidney(1) Left renal calculi, (2) double renal abscess, (3) hypokalemia, (4) hyponatremia, (5) hypochloremia
Patient 6Y44FemaleMedullary sponge kidney(1) Right renal calculi, (2) Hashimoto’s thyroiditis, (3) chronic superficial gastritis, (4) dyslipidemia, (5) polypofgallbladder
Patient 7Y71MaleMedullary sponge kidney(1) Left renal calculi, (2) left renal abscess, (3) right pelvic effusion, (4) right spontaneous pneumothorax, (5) liver cyst, (6) gallstone
Patient 8Y42MaleMedullary sponge kidney(1) Double renal calculi, (2) double renal cyst, (3) greater occipital neuralgia, (4) hypertension
Patient 9Y5FemaleMedullary sponge kidney(1) Inherited metabolic diseases, (2) low calcium tetany, (3) hypokalemia, (4) hyponatremia, (5) hypocalcemia, (6) malnutrition iii, (7) dwarfism, (8) hypoparathyroidismMutations in ACAN, ABCC8
Patient 10Y32FemaleMedullary sponge kidney(1) Double renal calculi, (2) left upper ureteral calculi
Patient 11Y46MaleMedullary sponge kidney(1) Double renal cyst, (2) left uronephrosis, (3) hypokalemia, (4) hypertension, (5) pituitary microadenoma
Patient 12Y69FemaleMedullary sponge kidney(1) Septic stock, (2) double renal calculi, (3) left renal cyst, (3) right ureteral calculi, (4) renal insufficiency, (5) urinary infection, (6) anemia
Patient 13Y27FemaleMedullary sponge kidney(1) Left renal calculi, (2) right ovarian teratoma, (3) left breast fibroadenoma, (4) breast hyperplasia
Patient 14Y2MaleMedullary sponge kidney(1) Double renal calculi, (2) bladder calculi, (3) uroschesis
Patient 15Y39MaleMedullary sponge kidney(1) Left forearm schwannoma, (2) multiple dermoid cysts, (3) gallbladder polyp
Patient 16Y63MaleMedullary sponge kidney(1) Double renal calculi, (2) left renal cyst
Patient 17Y33FemaleMedullary sponge kidney(1) Left renal calculi, (2) left renal artery stenosis, (3) hypertension, (4) hyperuricemia, (5) dyslipidemia