Effect of Thymoquinone on Renal Damage Induced by Hyperlipidemia in LDL Receptor-Deficient (LDL-R^-/^-) Mice

Figure 7

Schematic diagram representing how TQ protects against hyperlipidemia-induced renal damage in mice. TQ: thymoquinone; NOX4: NADPH oxidase 4; CAT: catalase; NRF2: nuclear factor erythroid 2–related factor 2; HO-1: heme oxygenase-1; MMP: matrix metalloproteinase; TNF-α: tumor necrosis factor α; IL: interleukin; PI3K: phosphoinositide 3-kinase.