Polyacetylenes from Codonopsis lanceolata Root Induced Apoptosis of Human Lung Adenocarcinoma Cells and Improved Lung Dysbiosis

Figure 2

Effect of CLP on the migration, invasion, and colony formation of A549 cells. (a) Cell migration was determined by a wound healing assay. (b) Cell invasion was determined by a Transwell assay. A549 cells were treated with CLP (2.5, 5, and 10 μg/mL) or DDP (5 μg/mL) for 48 h, respectively. (c) The number of colonies of the A549 cells, which were treated with CLP (2.5, 5, and 10 μg/mL) or DDP (5 μg/mL) for 7 days, was counted under low-magnification light microscope (×100). (d) The quantitative results of migration, invasion, and colony formation assay. Data were expressed as . The groups marked with different letters suggested significant differences, .

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