Polyacetylenes from Codonopsis lanceolata Root Induced Apoptosis of Human Lung Adenocarcinoma Cells and Improved Lung Dysbiosis

Figure 5

Antitumor effects of CLP on the A549 tumor-bearing mouse model. The nude mice were randomly divided into five subgroups as follows: model, treated with saline; CLP-L, treated with 10 mg/kg of CLP; CLP-M, treated with 20 mg/kg of CLP; CLP-H, treated with 40 mg/kg of CLP; and DDP, treated with 5 mg/kg of DPP. (a) Tumor growth was monitored every 5 days by using the IVIS Lumina LT imaging system. (b) Tumor growth in the mouse model. (c) Morphological observation of tumor tissue (black arrows). (d) Body weight changes. Data were expressed as . The groups marked with different letters suggested significant differences, .

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