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| Pathway ID | Description | value | Gene count | Genes |
|
| hsa04060 | Cytokine-cytokine receptor interaction | 3.81E-54 | 109 | XCR1/OSM/CXCL12/BMP5/TNFRSF17/CXCR6/IL2RB/LEPR/GDF15/FASLG/PPBP/INHBE/INHBC/GHR/IL15/
ACVR2A/CD70/PF4V1/IL18/GDF9/TNFRSF13B/IL2RG/GDF1/LIFR/GDF5/IL23A/IL10/IL1R2/IL11/IL1R1/
TNFSF9/GDF11/CXCR3/IL18RAP/IL17B/IFNB1/CCR5/IL9R/IL17RE/EPOR/CX3CR1/TNFRSF8/IL1RL1/
TNFRSF10D/IL5RA/TNFRSF6B/IL1RL2/ACVR1C/IL7R/CCL25/IL12A/CCR4/PF4/TNF/IL3RA/MSTN/CCR10/
CCL1/IL33/CCR6/CCL28/GH1/BMP6/CTF1/EBI3/PRL/CSF3/IL13/INHBB/LTA/TSLP/BMP10/MPL/TNFRSF4/
IL17D/CXCL8/TNFSF14/CCR1/IL2RA/IL24/IL17RB/GDF3/NODAL/IFNLR1/CXCL13/CXCL3/OSMR/CCL24/
CCL27/NGFR/CXCL16/INHA/IL7/IL27/CRLF2/TNFRSF11A/IFNK/IL13RA2/BMPR1B/CXCL11/AMHR2/CSF2/
ACKR4/IL12RB2/BMP2/CXCL5/IL12B/LEP/CXCL14 |
| hsa04630 | JAK-STAT signaling pathway | 5.75E-20 | 49 | OSM/PDGFRA/STAT5A/IL2RB/EGFR/LEPR/SOCS5/SOCS3/GHR/IL15/IL2RG/LIFR/IL23A/IL-10/HRAS/IL11/
IFNB1/IL9R/EPOR/JAK3/IL5RA/IL7R/PDGFB/IL12A/IL22RA2/IL3RA/SOCS2/GH1/CTF1/PRL/CSF3/IL13/TSLP
/BCL2L1/MPL/IL17D/IL2RA/IL24/IFNLR1/OSMR/EGF/IL7/CRLF2/IFNK/IL13RA2/CSF2/IL12RB2/IL12B/LEP |
| hsa04061 | Viral protein interaction with cytokine and cytokine receptor | 8.36E-17 | 35 | XCR1/CXCL12/IL2RB/PPBP/PF4V1/IL18/IL2RG/IL10/CXCR3/IL18RAP/CCR5/CX3CR1/
TNFRSF10D/CCL25/CCR4/PF4/TNF/CCR10/CCL1/CCR6/CCL28/LTA/CXCL8/TNFSF14/CCR1/IL2RA/IL24/
CXCL13/CXCL3/CCL24/CCL27/CXCL11/ACKR4/CXCL5/CXCL14 |
| hsa05133 | Pertussis | 2.78E-15 | 29 | NLRP3/RELA/TRAF6/MAPK3/CASP7/CD14/RHOA/NFKB1/GNAI2/NOD1/IL23A/IL10/IRF1/TLR4/C4B/C2/C1S/
JUN/PYCARD/IL12A/TNF/TICAM1/C5/GNAI1/CXCL8/SERPING1/C4BPA/CXCL5/IL12B |
| hsa04650 | Natural killer cell mediated cytotoxicity | 1.56E-13 | 36 | KLRD1/SH2D1B/GZMB/PRF1/FASLG/MAPK3/MICA/NCR1/MICB/HLA-A/KLRC1/FCGR3A/KLRK1/HRAS/
HCST/FYN/KIR3DL1/IFNB1/HLA-C/RAET1E/TNF/KIR2DL3/RAC2/NCR2/RAC3/TYROBP/KIR2DL1/CD244/
KIR3DL2/HLA-G/SHC4/SH2D1A/FCER1G/SHC3/ULBP1/CSF2 |
| hsa04612 | Antigen processing and presentation | 4.13E-13 | 27 | KLRD1/HSPA5/CALR/PDIA3/HSP90AB1/RFXANK/CTSS/CD8A/HLA-A/KLRC1/HSPA1B/TAPBP/KIR3DL1/PSME1/PSME2/HLA-C/HSP90AA1/HSPA1A/TNF/KIR2DL3/HSPA2/HSPA6/KIR2DL1/KIR3DL2/HLA-G/HLA-DMA/CD74 |
| hsa05417 | Lipid and atherosclerosis | 1.37E-12 | 46 | HSPA5/DDIT3/ATF4/NLRP3/HSP90AB1/RELA/TRAF6/XBP1/FASLG/MAPK3/CASP7/VCAM1/VLDLR/CD36/CD14/
IL18/RHOA/NFKB1/APOA1/CAMK2A/HSPA1B/HRAS/TLR4/OLR1/IFNB1/CYBB/HSP90AA1/JUN/PYCARD/IL12A
/HSPA1A/RXRA/TNF/TICAM1/ABCA1/CASP6/HSPA2/HSPA6/BCL2L1/ABCG1/CXCL8/CXCL3/SELE/LBP/MMP9/IL12B |
| hsa04151 | PI3K-Akt signaling pathway | 5.98E-11 | 59 | OSM/PDGFRA/PKN1/THBS1/KITLG/ATF4/HSP90AB1/RELA/IL2RB/EGFR/VEGFA/FGF17/FASLG/MAPK3/ATF2/GHR/FGFR4/FLT3/IL2RG/FGFR1/NFKB1/TNC/HRAS/TLR4/IFNB1/EIF4EBP1/EPOR/HSP90AA1/JAK3/VEGFC/IL7R/PDGFB/RXRA/FGF5/IL3RA/NR4A1/CDK6/GH1/ITGB3/
PRL/CSF3/HGF/PDGFC/PGF/BCL2L1/FGF18/ANGPT1/FLT4/IGF1/IL2RA/OSMR/EGF/NGFR/IGF2/IL7/
FGF10/VTN/ANGPT4/FGF2 |
| hsa04010 | MAPK signaling pathway | 9.65E-11 | 52 | XCR1/CXCL12/NFKBIB/RELA/CXCR6/CRKL/PPBP/MAPK3/PF4V1/RHOA/NFKB1/GNAI2/HRAS/GSK3A/CXCR3/
CCR5/CX3CR1/JAK3/CCL25/CCR4/PF4/CCR10/CCL1/CCR6/CCL28/RAC2/RAC3/GNAI1/CXCL8/CCR1/SHC4/
CXCL13/CXCL3/CCL24/CCL27/CXCL16/SHC3/CXCL11/CXCL5/CXCL14 |
| hsa04062 | Chemokine signaling pathway | 1.01E-10 | 40 | PKN1/NFKBIB/NLRP3/HSP90AB1/RELA/TRAF6/NLRP7/MAPK3/IL18/DEFA4/RHOA/NFKB1/NOD1/TLR4/NLRP6/
DEFA3/NOD2/IFNB1/CYBB/DEFA1/MEFV/NAMPT/HSP90AA1/JUN/NLRP12/PYCARD/GABARAP/TNF/TICAM1/
RIPK2/DEFA1B/CARD9/BCL2L1/CAMP/NLRC4/CXCL8/GBP7/CXCL3 |
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