Comparative Insights into the Skin Beneficial Properties of Probiotic Lactobacillus Isolates of Skin Origin

Table 1

Summary on the skin beneficial properties of the three conditioned mediums.

Skin beneficial activities	Relative activities
	LP202	LF101	LPP401
In vitro free radical scavenging activities
Superoxide radical ion scavenging	++	+++	+++
Nitrite ion scavenging	++	++	+++
Anti-inflammatory activities in macrophages
Attenuation of LPS-induced ROS	+	+++	+++
Attenuation of LPS-induced NO	++	+++	+++
Skin whitening activities
Antityrosinase activity	++	++	+++
Attenuation of melanin in melanoma cells	+	+++	+++
Skin barrier function-enhancing activity
Enhancement of cornified envelope formation in keratinocytes	+	++	+++
Antiaging enzyme activities
Antihyaluronidase activity	+	+	+++
Antielastase activity	+++	+++	+++
Collagen production-promoting activity
Enhancement of collagen synthesis in fibroblasts	—	++	++

+: weak; ++: moderate; +++: strong; –: no activity.