Review Article

Effect of Different Membranes on Vertical Bone Regeneration: A Systematic Review and Network Meta-Analysis

Table 3

Characteristics of the included studies.

Study IDMembranePatients ()/implants ()No. of patients (mean age; range of age) (in years)Bone graft materialsFollow-up time (months)Vertical bone gain (mm/%)GBR/GTR

Ronda et al. [33]Titanium-reinforced, d-PTFE12/3823 (49.60/30–78)Autologous bone and mineralized bone allograft (1 : 1)6GBR
Titanium-reinforced
e-PTFE
11/40
Pruthi et al. [13]e-PTFE17/1717 (56.50/35–75)NA12GTR
CM17/17
Moses et al. [15]CM28/5328 (50.50/NA)Autogenous bone chips mixed with either bovine bone mineral6–8GBR
e-PTFE17/3417 (55.40/NA)
Annen et al. [11]CCM9/99 (50.20/NA)Bovine bone mineral granules6GBR
CM9/9
Carpio et al. [16]CM23/2348 (NA/NA)Anorganic bovine bone plus; autogenous bone chips (1 : 1)6GBR
e-PTFE25/25
Lee et al. [22]CM14/1428 (53.30/31–75)Xenograft bone substitutes4GBR
CCM14/14
Scheyer et al. [35]CM19/1940 (NA/18–70)Demineralized allograft6GBR
CCM21/21Deproteinized bovine bone mineral
Arbab et al. [45]CM12/1212 (53.00/25–73)Cancellous allograft and bovine-derived xenograft4GBR
d-PTFE12/1212 (52.00/30–73)
Naenni et al. [27]CM13/1327 (51.85/NA)Demineralized bovine bone mineral6GBR
Titanium-reinforced; e-PTFE14/14
Cucchi et al. [46]d-PTFE19/5436 (52.00/NA)Autogenous bone and bone allograft (1 : 1)12GBR
TM + CCM17/44
Lim et al. [23]CCM12/1212 (53.83/NA)Collagenated porcine bone4GBR
CM14/1414 (48.14/NA)Collagenated bovine bone
Maiorana et al. [34]Titanium-reinforced; d-PTFE5/55 (54.20/38–65)Autogenous bone and deproteinized bovine bone mineral particles (1 : 1)8GBR
TM5/5
Teparat et al. [19]e-PTFE10/910 (NA/40–65)NA9GBR
PLA10/10
Blumenthal [17]e-PTFE12/1212 (NA/31–80)NA12GBR
CM12/12
Christgau et al. [47]PLA 910NA/1611 (40.40/23–59)NA12GTR
e-PTFENA/14
Merli et al. [28]CM11/4211 (44.60/29–59)Autologous bone72GBR
Titanium-reinforced; e-PTFE10/5510 (49.90/36–69)
Kim et al. [48]PLA 9108/88 (NA/NA)NA6GTR
e-PTFE8/8
Karapataki et al. [20]PLA10/1019 (43.00/NA)NA12GTR
e-PTFE9/9
Choi et al. [32]TM15/17100 (57.10/20–82)An allograft bone6GBR
TM + CCM56/72
TM + CM29/40
Friedmann et al. [26]CCM17/3737 (NA/24–69)A coagulum was formed by the calcium phosphate grafting material6/GBR
CM20/36
Tal et al. [24]CCM52/5252 (46.00/20–70)Deproteinized bovine bone mineral6GBR
CM52/52
Weltman et al. [21]PLA30/1630 (NA/26–64)NA12GBR
e-PTFE30/14
Atef et al. [49]CM20/1020 (NA/20–60)Autogenous and anorganic bovine bone mineral bone mixture (1 : 1)6GBR
TM20/10
Jung et al. [30]PEG57/57117 (48.70/19–77)A synthetic bone filler6GBR
BG57/57
Jung et al. [31]PEG19/1919 (48.00/32–72)A natural bone mineral of bovine origin6GBR
CM18/1818 (54.00/23–80)
Cucchi et al. [14]TM15/3430 (NA/NA)Autogenous bone and bone xenograft (1 : 1)6GBR
TM + CCM15/37
Becker et al. [25]CCM23/4123 (44.90/NA)Natural bone mineral4GBR
CM26/3726 (42.40/NA)