Research Article

Determination of Phenolic Compounds and Bioactive Potential of Plum (Prunus salicina) Peel Extract Obtained by Ultrasound-Assisted Extraction

Figure 2

Cytotoxic effects of plum peel extract (PPE) on cancer cell lines in vitro. (a) Results of MTT cytotoxicity assay showing increase in growth inhibition of DLD-1, HCT-116, MDA-MB-231, and PC3 cells with increasing concentration of PPE. Doxorubicin was used as a positive control. Error bars show standard error of mean of four wells. (b) IC50 of PPE, values were obtained by nonlinear regression curve fitting of normalized cell survival; error bars represent 95% confidence interval. (c) Phase contrast microscopy, images were obtained after 72 hours of treatment with PPE; scale bar represents 100 μm.
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