Overexpression of CISD1 Predicts Worse Survival in Hepatocarcinoma Patients

Figure 1

The mRNA expression level of CISD1 in human pan-cancer. (a) Increased or decreased CISD1 mRNA expression in human pan-cancer data of TCGA. (b) Increased or decreased CISD1 mRNA expression in human pan-cancer data of integrated TCGA and GETx. (c) The mRNA expression of CISD1 was significantly higher in LICH samples than in the unpaired nontumor samples. (d) The mRNA expression of CISD1 was significantly higher in LICH samples than in the paired nontumor samples. (e, f) Increased CISD1 mRNA expression in datasets of hepatocarcinomas compared with normal tissues in the Oncomine database. Immunohistochemical results of the HPA database showed that CISD1 protein was (g) moderately expressed in hepatocytes and (h) strongly expressed in hepatocarcinoma cells.

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