IL-17A Promotes the Migration, Invasion and the EMT Process of Lung Cancer Accompanied by NLRP3 Activation

Figure 5

NLRP3 was activated in IL-17A treated lung cancer cells. (a) Western blot of NLRP3-related markers were increased in A549 followed by IL-17A stimulated. (b) Quantification of results from A. (c) Caspase-1 activity was increased in IL-17A group of A549. (d) The concentration of IL-1β in A549 was increased after IL-17A treated. (e) The expression of NLRP3-related markers in each group of H1299 cells. (f) Quantification of results from A. (g) Caspase-1 activity was increased after IL-17A stimulation. (h) IL-1β concentration in H1299 was increased after IL-17A treated. Data shown are mean ± SD. It is one way ANOVA was used in statistical analysis. Error bars, mean ± SD. P <0.05; P <0.01; P <0.001, ns, non-signifcant; SD, standard deviation.

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