SLC6A14 Depletion Contributes to Amino Acid Starvation to Suppress EMT-Induced Metastasis in Gastric Cancer by Perturbing the PI3K/AKT/mTORC1 Pathway

Table 1

Correlation between SLC6A14 expression and the clinicopathological features of gastric cancers.

Clinicopathological features		SLC6A14 expression				value
		Low	High	PR (%)
		+	++	+++
Age						0.30
<50years	53	18	15	20	66.8
≥50 years	50	21	10	19	59.3
Gender						0.71
Male	48	19	14	15	60.1
Female	55	20	15	20	63.2
Distant metastasis						0.009
M0	52	36	7	9	30.2
M1	51	3	16	32	94.0
Depth of invasion						0.023
Tis-1	23	20	1	2	13.09
T2	25	9	10	6	62.0
T3	29	5	19	5	82.6
T4	26	5	10	11	80.0
Venous invasion						0.033
—	51	24	13	14	50.1
+	52	15	29	8	71.4
Lymph node metastasis						0.035
N0	24	18	3	3	25.2
N1	26	12	11	3	53.4
N2	28	4	18	6	85.5
N3	25	5	12	8	86.0
Lymphatic invasion						0.021
—	48	25	16	7	41.5
+	55	14	24	17	74.5
Tumor differentiation						0.75
Well or moderate	50	20	18	12	60.0
Poor	53	19	18	16	64.0
AJCC staging						0.65
Stage I	25	18	4	3	28.0
Stage II	26	12	10	4	53.8
Stage III	24	6	12	6	75.0
Stage IV	28	3	10	15	89.3

PR (%): positive rate; test was executed to assess the association between SLC6A14 expression and the pathological features of GC patients. .